Put Oral Antibiotics for Gram-Positive Bacteremia in Perspective

Questions may crop up about whether to step down to oral antibiotics for gram-positive bacteremia.

We’re used to treating bacteremia with IV antibiotics for several weeks for most cases of Staphylococcus, Streptococcus, and Enterococcus spp.

Stepping down to oral antibiotics can reduce cost, length of stay, and catheter-associated infections. But balance it with concerns for adherence, follow-up, and limited evidence.

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